General
Preferred name
NVS-MALT1
Synonyms
NVS_MALT1 ()
P&D ID
PD127640
CAS
2993517-26-1
Tags
probe
available
free of charge
Probe info
Probe type
P&D approved
experimental probe
Probe selectivity
protein-selective
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Orthogonal probes
2
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
MOA
Inhibitor
(Chemical Probes.org)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
Chemical Probes.org
EUbOPEN Chemogenomics Library
High-quality chemical probes
Open Science Probes
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
3
Molecular Weight
573.14
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
3
cLogP
4.72
TPSA
105.9
Fraction CSP3
0.46
Chiral centers
2.0
Largest ring
6.0
QED
0.44
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
Allosteric inhibitor
Protein Family
interface between caspase and Ig3 domains
Protease
Control name
NVS-MALT1-C
Target
MALT1
Target class
Enzyme
Target subclass
Peptidase
Recommended Cell Concentration
1 uM
Source data
